In a study that investigates the challenges of disseminating clinical research findings in peer-reviewed biomedical journals, Yale School of Medicine researchers have found that fewer than half of a sample of trials primarily or partially funded by the National Institutes of Health (NIH) were published within 30 months of completing the clinical trial. These findings appear in the January issue of the British Medical Journal, which focuses on the topic of unpublished evidence.

"When research findings are not disseminated, the scientific process is disrupted and leads to redundant efforts and misconceptions about clinical evidence," said Joseph Ross, M.D., first author of the study and a Yale assistant professor of medicine. "Such inaction undermines both the trial in question and the evidence available in peer-reviewed medical literature. This has far-reaching implications for policy decisions, and even institutional review board assessments of risks and benefits associated with future research studies."

Ross and co-authors performed a cross-sectional analysis of NIH-funded clinical trials registered within ClinicalTrials.gov, a trial registry and results database maintained by the U.S. National Library of Medicine. All trials in the study sample were registered after September 30, 2005 and completed by December 31, 2008, allowing at least 30 months for publication following completion of the trial. They found that overall fewer than half of NIH-funded trials in the sample were published in a peer-reviewed, MEDLINE-indexed biomedical journal within 30 months of trial completion. They also found that one-third of trials remained unpublished 51 months after completion.

Ross said that there may be many reasons for lack of publication, such as not getting accepted by a journal or not prioritizing the dissemination of research findings. Still, he said, there are alternative methods for providing timely public access to study results, including the results database at ClinicalTrials.gov that was created in response to Federal law. "Steps must be taken to ensure the timely dissemination of publicly funded research so that data from all those who volunteer are available to inform future research and practice," Ross said.

While this study was focused on trials funded by NIH, Ross said that similar problems with non-publication and delayed publication of research findings have been described among trials funded by the pharmaceutical and medical device industries, as well as by non-profit organizations. "This suggests that the current culture of research needs to prioritize the timely public dissemination of research findings, ideally via peer-reviewed journals, for research funded by both public and private sources," said Ross. "More work needs to be done to better understand impediments to publication."

A University of New Hampshire researcher has discovered that a former Yale professor who espoused pro-eugenic beliefs manipulated his research findings so he could conclude that his Wisconsin home town was overflowing with mentally and morally "unfit" people. Benjamin Harris, professor of psychology and affiliate professor of history at UNH, has found that Yale psychologist Arnold Gesell manipulated the photographic record by selectively choosing photos to make his pro-eugenic case in his piece "The Village of a Thousand Souls." Published in 1913 in "The American Magazine," the widely read article accused Gesell's hometown of Alma, Wisc., of being overrun with "hereditary defectives." Harris's discovery of Gesell's deception is detailed in the most recent issue of the journal History of Psychology, published by the American Psychological Association.

In the 1940s and 1950s, Gesell was widely regarded as the nation's foremost authority on child rearing and development, and developmental quotients based on his development schedules were widely used as an assessment of children's intelligence, according to the Encyclopedia of Psychology. "Until Benjamin Spock emerged in the late 1940s as an advice-giver, Arnold Gesell's guides to child development were the manuals of choice for the nation's mothers," Harris said.

In "The Village of a Thousand Souls," Gesell called for the observation and segregation of the "unfit" as a eugenic measure. Harris discovered that Gesell manipulated the photographic record to support his thesis, even substituting a photo of a different town because it showed a "saloon" sign that was lacking in Alma. Gesell's research relied on his father's collection photographs documenting decades of life in Alma, Wisc. Gesell's father, Gerhard Gesell, owned photo studio in the town for many years, and his collection included images of streets of respectable-looking buildings, parades of automobiles on those streets for holidays, and groups of children and adults enjoying everyday life in a riverside town.

"What Gesell selected, however, were images selected to support his thesis that the town was degenerate," Harris said.  For example, Gesell juxtaposed two photos. One shows a seeming tramp in front of a shack, identified as "Evidence of a Feeble Mind." The second photo is of a tidy frame house, well-kept yard, and four well-dressed people enjoying leisure time. The second photo is captioned "Evidence of a Vigorous Mind."

Harris discovered that the first photograph alleging "evidence of a feeble mind" was actually a photo of one of Alma's early settlers, Abraham Schmocker, taken in the mid-1800s. "An alternate view of Schmocker also was available, showing him holding what appears to be a pet cat. That photo shows a bucket, washtub and washboard, making Schmocker seem to be taking care of himself. Because it's more of a close-up, one can also see more easily that it is a roughly made cabin—rather than a neglected house. But Arnold used the less humanizing photo and placed it next to one of a more urban family, taken 20 to 25 years later," Harris said. Moreover, the unidentified home in the second photo that purported to show "evidence of a vigorous mind" was apparently thought to be the Gesell house, which infuriated local residents.

In another instance of research manipulation, Gesell used a photo of a neighboring town, Reeds Landing, Minn., that was purported to be "Main Street of the Village of a Thousand Souls." "Why substitute a photo from another town if the article is about Alma's qualities? The mystery of this photo substitution lasts only long enough for one to see the sign above the heads of the groups on the right side of the street: SALOON," said Harris, who could not find a single photo of Alma that showed a saloon in the Gerhard Gesell photo collection at the Wisconsin Historical Society. "Thus Arnold Gesell manipulated the photographic evidence to fit the sociological message that saloons were both a symptom and a cause of feeblemindedness," he said.

Although Gesell did not advocate eugenic sterilization, Harris said, his article spoke to the discussion taking place in states over possible eugenic legislation. These included Wisconsin, where Gesell grew up and where the legislature debated and passed two eugenic restriction laws in 1913. One mandated medical exams for those wishing to marry, which was challenged in court but took effect the following year. The other authorized the sterilization of the institutionalized mentally retarded and state prison inmates.

Even during a recession, pharma is still the nation's third most profitable sector. Here are some of the dirty tricks it employs to stay on top. Read the AlterNet article here.

Individuals with competing cultural values disagree about what most scientists believe

Suppose a close friend who is trying to figure out the facts about climate change asks whether you think a scientist who has written a book on the topic is a knowledgeable and trustworthy expert. You see from the dust jacket that the author received a Ph.D. in a pertinent field from a major university, is on the faculty at another one, and is a member of the National Academy of Sciences. Would you advise your friend that the scientist seems like an "expert"?

If you are like most people, the answer is likely to be, "it depends." What it depends on, a recent study found, is not whether the position that scientist takes is consistent with the one endorsed by a National Academy. Instead, it is likely to depend on whether the position the scientist takes is consistent with the one believed by most people who share your cultural values.

This was the finding of a recent study conducted by Yale University law professor Dan Kahan, University of Oklahoma political science professor Hank Jenkins-Smith and George Washington University law professor Donald Braman that sought to understand why members of the public are sharply and persistently divided on matters on which expert scientists largely agree.

"We know from previous research," said Dan Kahan, "that people with individualistic values, who have a strong attachment to commerce and industry, tend to be skeptical of claimed environmental risks, while people with egalitarian values, who resent economic inequality, tend to believe that commerce and industry harms the environment."

In the study, subjects with individualistic values were over 70 percentage points less likely than ones with egalitarian values to identify the scientist as an expert if he was depicted as describing climate change as an established risk. Likewise, egalitarian subjects were over 50 percentage points less likely than individualistic ones to see the scientist as an expert if he was described as believing evidence on climate change is unsettled.

Study results were similar when subjects were shown information and queried about other matters that acknowledge "scientific consensus." Subjects were much more likely to see a scientist with elite credentials as an "expert" when he or she took a position that matched the subjects' own cultural values on risks of nuclear waste disposal and laws permitting citizens to carry concealed guns in public.

"These are all matters," Kahan said, "on which the National Academy of Sciences has issued 'expert consensus' reports." Using the reports as a benchmark," Kahan explained that "no cultural group in our study was more likely than any other to be 'getting it right'," i.e. correctly identifying scientific consensus on these issues. They were all just as likely to report that 'most' scientists favor the position rejected by the National Academy of Sciences expert consensus report if the report reached a conclusion contrary to their own cultural predispositions."

In a separate survey component, the study also found that the American public in general is culturally divided on what "scientific consensus" is on climate change, nuclear waste disposal, and concealed-handgun laws.

"The problem isn't that one side 'believes' science and another side 'distrusts' it," said Kahan referring to an alternate theory of why there is political conflict on matters that have been extensively researched by scientists.

He said the more likely reason for the disparity, as supported by the research results, "is that people tend to keep a biased score of what experts believe, counting a scientist as an 'expert' only when that scientist agrees with the position they find culturally congenial."

Understanding this, the researchers then could draw some conclusions about why scientific consensus seems to fail to settle public policy debates when the subject is relevant to cultural positions.

"It is a mistake to think 'scientific consensus,' of its own force, will dispel cultural polarization on issues that admit scientific investigation," said Kahan. "The same psychological dynamics that incline people to form a particular position on climate change, nuclear power and gun control also shape their perceptions of what 'scientific consensus' is."

"The problem won't be fixed by simply trying to increase trust in scientists or awareness of what scientists believe," added Braman. "To make sure people form unbiased perceptions of what scientists are discovering, it is necessary to use communication strategies that reduce the likelihood that citizens of diverse values will find scientific findings threatening to their cultural commitments."

The first academic analysis of the 1500 documents unsealed in recent litigation against the pharmaceutical giant Wyeth (now part of Pfizer) reveals unprecedented insights into how pharmaceutical companies use ghostwriters to insert marketing messages into articles published in medical journals. Dr. Adriane Fugh-Berman, associate professor in the Department of Physiology at Georgetown University Medical Center in Washington DC, analyzed dozens of ghostwritten reviews and commentaries published in medical journals and journal supplements that were used to promote unproven benefits and downplay harms of Prempro—a brand of menopausal hormone therapy (HT)—and to cast competing therapies in a negative light. These articles were widely circulated to drug reps and doctors to disseminate the company's marketing messages. The analysis appears in this week's PLoS Medicine.

Wyeth used a medical education & communication company, DesignWrite, to produce ghostwritten articles in order to mitigate the perceived risks of breast cancer associated with HT, to defend the unsupported cardiovascular ''benefits'' of HT, and to promote off-label, unproven uses of HT such as the prevention of dementia, Parkinson's disease, vision problems, and wrinkles, writes Fugh-Berman.

The analysis revealed that DesignWrite was paid US$25,000 to ghostwrite articles reporting clinical trials, including four manuscripts on the HOPE trials of low-dose Prempro. DesignWrite was also assigned to write 20 review articles about the drug, for which they were paid US$20,000 each.

The analysis concludes that "Given the growing evidence that ghostwriting has been used to promote HT and other highly promoted drugs, the medical profession must take steps to ensure that prescribers renounce participation in ghostwriting, and to ensure that unscrupulous relationships between industry and academia are avoided rather than courted."

In July 2009, PLoS Medicine, represented by the public interest law firm Public Justice, and The New York Times acted as intervenors in litigation against menopausal hormone manufacturers by 14,000 plaintiffs whose claims related to the development of breast cancer while taking the hormone therapy Prempro (conjugated equine estrogens). This resulted in a US federal court decision to release approximately 1500 documents to the public. The Wyeth Ghostwriting Archive is available at http://www.plosmedicine.org/static/ghostwriting.action or through the UCSF Drug Information Document Archive at http://dida.library.ucsf.edu/documents.jsp

For those of you who wish to pursue the different jobs in psychology, here is an extensive list to choose from.

What the Experts Still Don't Know (podcast)
This month the British Psychological Society published the 150th issue of its Research Digest. To celebrate, they asked 23 world-renowned psychologists the following question: What is one nagging thing that you still don’t understand about yourself? (full article) A few touched on consciousness. But many wrote about the conundrum of how understanding behavior does nothing to change behavior.

60-Second Psych from Scientific American podcasts
9 November 2009

The Holy Grail of the Unconscious — New York Times article (login required) about the publication of Jung's Red Book (link to publisher's page) due out in October 2009.

A study by three Kansas State University graduate students finds that the 18- to 24-year-old demographic became more politically active during the 2008 U.S. election season through the use of new media, but that the young adults were not necessarily more knowledgeable about politics. The K-State study examined young adults' media consumption and the effects of new media on their political knowledge and political activism. While the study showed that 18- to 24-year-olds were actively engaging in politics through media such as blogs and YouTube, their involvement did not increase their knowledge.

The K-State researchers conducting the study, all master's students in journalism and mass communications, were Keunyeong Kim, and Sookyong Kim, both from Manhattan, and Chance York, Wamego. William Adams, K-State professor of journalism and mass communications, was the project adviser. The research was presented at the 2009 Association for Education in Journalism and Mass Communication convention. "Politicians in general are so reliant on political polling, but politicians are not examining how much the voter knows about the issues they're voting on," York said.

The study targeted the 18- to 24-year-old demographic and examined the group's usage of new media. The researchers surveyed more than 160 undergraduate students in February about their use of both traditional media sources, including radio campaign commercials, and new media sources, like blogs, to obtain information about presidential candidates and their campaign issues. "We were trying to find what information sources 18- to 24-year olds were looking at and how that might have affected their political activism and their level of political knowledge," York said.

The survey's measures for political activism included yes or no questions that dealt with traditional and online forms of political involvement. The traditional methods of activism included volunteering for a presidential candidate's campaign or attending a candidate's rally, while online forms of involvement included checking a presidential candidate's campaign Web site. The measure for political knowledge was similar to a current events quiz with questions like the name of the U.S. secretary of defense. The survey also measured the demographics of the students, including their political affiliation and ideology and whether they voted in the 2008 election.

"We found that the students were really politically active," York said. "They talked about the campaigns with their friends, and a lot of people got online on a social networking site to talk about the campaigns. Not many wrote blogs, but a considerable amount kept up with blogs." The study also found that most students were not politically knowledgeable, York said. For instance, many students did not know what Guantanamo Bay was; some said it was a Caribbean resort.

There also was a set of people that were both politically active and knowledgeable, and there was a high correlation between those two variables and voting. "People who were actually voting were both active and knowledgeable, and that wasn't affected by whether the student was a Democrat or Republican, or liberal or conservative," York said.

Additionally, the study indicated that among the 18- to 24-year-old demographic, the individuals who voted were not the ones using new media to obtain political information. The researchers also looked at the different types of new media, such as those that would be considered "gatekeepers," where an editorial member controls the flow of knowledge, and "gatewatchers," where information flows more freely.

The study showed that the more people used new media that would be considered "gatewatched," such as blogs, the more likely they were to be politically active -- but not politically knowledgeable. New media that would be "gatekept," such as online news articles, had less of an impact on political activism and no significant effect on political knowledge. Survey respondents' use of traditional media did not play a significant role in their political activism or political knowledge.

York said the study has limitations, particularly since the students were not selected from a random sample. "What we can't say is that this is true for all 18-to 24-year-olds, and statistically we can't make a significant inference," York said. "However, there is not a lot of research in this area, and so trying to forge out that path is a good start."

"[...] the common strategies include dismissing as "junk science" peer-reviewed studies showing a link between their products and disease; paying scientists to produce pro-industry studies; sowing doubt in the public's mind about the harm caused by their products; intensive marketing to children and adolescents; frequently rolling out supposedly "safer" products and vowing to regulate their own industries; denying the addictive nature of their products; and lobbying with massive resources to thwart regulatory action."

Big Food Is Copying Big Tobacco's Disinformation Tactics, How Many Will Die This Time?
By Fen Montaigne
Posted 11 April 2009 on AlterNet

Oedipus Wrecked: Study Supporting the Mother of All Psychological Complexes Withdrawn by Brendan Borrell

A journal retracts a paper that supported the idea that your wife is likely to look like your mother, but others say that Freud's theory may still hold water

Trials showing a positive treatment effect, or those with important or striking findings, were much more likely to be published in scientific journals than those with negative findings, a new review from The Cochrane Library has found.

"This publication bias has important implications for healthcare. Unless both positive and negative findings from clinical trials are made available, it is impossible to make a fair assessment of a drug's safety and efficacy," says lead researcher, Sally Hopewell of the UK Cochrane Centre in Oxford, UK.

The international team of researchers carried out a systematic review of all the existing research in this area. In addition to showing that negative results were published less often, they found that if these results were eventually published, they would take between one and four more years to appear in journals than studies showing positive results.

Results from one of the five studies in the review indicated that investigators and not editors might be to blame. The reasons most commonly given for not publishing were that investigators thought their findings were not interesting enough or did not have time. "The registration of all clinical trial protocols before they start should make it easier to identify where we are missing results," says Kay Dickersin from Johns Hopkins University in Baltimore, USA, another of the researchers on this project.

One of the other researchers, Kirsty Loudon, based in Scotland, adds, "Registration of trials and their results would help people conducting systematic reviews to look at both published and unpublished evidence, to reach reliable conclusions."

The researchers say their study also highlights the need for a worldwide commitment to the disclosure of the findings of clinical trials. Mike Clarke of Trinity College Dublin in Ireland, says, "The World Health Organisation recently found widespread support for the development of such a process."

Andy Oxman from the Norwegian Knowledge Centre for Health Services concludes, "Healthcare decisions need to be based on all the evidence, not just the most exciting results."

Gait recognition software could improve security surveillanceat a distance

Biometrics is commonly associated retinal scans, iris recognition and DNA databases, but researchers in India are working on another form of biometrics that could allow law enforcement agencies and airport security to recognize suspects based on the way they were, their characteristic gait. The team reveals details of a comprehensive framework for gait recognition by computer in the inaugural issue of the Inderscience publication, the International Journal of Biometrics.

C. Nandini of the Vidya Vikas Institute of Engineering & Technology and C.N. Ravi Kumar of the S.J. College of Engineering in Mysore, India, explain that human gait typifies the motion characteristics of an individual. Viewed from the side, we each have a unique gait that makes us easily recognizable. They point out that a camera with a side view can record a set of key frames, or stances, as a person heads for the security desk at an airport, military installation or bank, for instance. Key frames over the person's complete walk cycle, can then be converted into silhouette form and statistical analysis using so-called Shannon entropy, together with height measurements and the periodicity of the gait usedto classify the person's gait. The gait of individuals checking in at an airport could then be compared with the database, perhaps even before they enter the airport concourse. Such data compared with CCTV footage might also be used to track suspect terrorists or criminals who may otherwise be disguising their features or be carrying forged documents.

The researchers emphasize that gait recognition has a significant advantage over more well-known biometrics, such as fingerprinting and iris scanning in that it is entirely unobtrusive and can be used to identify an individual potentially from a considerable distance. "The ability to identify a possible threat from a distance gives personnel a longer time frame in which to react before a possible suspect becomes a real threat," the researchers say.

They carried out initial tests on 20 people recorded walk in a straight line at normal speed and stride, back and forth in front of a video camera placed perpendicular to their path. They obtained good recognition rates using the Shannon entropy equation and the individuals' height. Recognition performance of the system was sensitive to changes in big viewing angle above ten degrees but was reasonably robust even when the individuals changed walking speed.

Scientists have revealed what may well be the first pervasive ‘rule’ of evolution. In a study published in the Proceedings of the National Academy of Sciences researchers have found evidence which suggests that evolution drives animals to become increasingly more complex.

Looking back through the last 550 million years of the fossil catalog to the present day, the team investigated the different evolutionary branches of the crustacean family tree. They were seeking examples along the tree where animals evolved that were simpler than their ancestors. Instead they found organisms with increasingly more complex structures and features, suggesting that there is some mechanism driving change in this direction.

“If you start with the simplest possible animal body, then there’s only one direction to evolve in – you have to become more complex,” said Dr Matthew Wills from the Department of Biology & Biochemistry at the University of Bath who worked with colleagues Sarah Adamowicz from the University of Waterloo (Canada) and Andy Purvis from Imperial College London.

“Sooner or later, however, you reach a level of complexity where it’s possible to go backwards and become simpler again. What’s astonishing is that hardly any crustaceans have taken this backwards route. Instead, almost all branches have evolved in the same direction, becoming more complex in parallel. This is the nearest thing to a pervasive evolutionary rule that’s been found. Of course, there are exceptions within the crustacean family tree, but most of these are parasites, or animals living in remote habitats such as isolated marine caves. For those free-living animals in the ‘rat-race’ of evolution, it seems that competition may be the driving force behind the trend. What’s new about our results is that they show us how this increase in complexity has occurred. Strikingly, it looks far more like a disciplined march than a milling crowd.”

Dr Adamowicz said: “Previous researchers noticed increasing morphological complexity in the fossil record, but this pattern can occur due to the chance origination of a few new types of animals. Our study uses information about the inter-relatedness of different animal groups – the ‘Tree of Life’ – to demonstrate that complexity has evolved numerous times independently.”

Like all arthropods, crustaceans’ bodies are built up of repeating segments. In the simplest crustaceans, the segments are quite similar - one after the other. In the most complex, such as shrimps and lobsters, almost every segment is different, bearing antennae, jaws, claws, walking legs, paddles and gills.

The American biologist Leigh Van Valen coined the phrase ‘Red Queen’ for the evolutionary arms race phenomenon. In Through the Looking-Glass Lewis Carroll’s Red Queen advises Alice that: “It takes all the running you can do, to keep in the same place.”

“Those crustacean groups going extinct tended to be less complex than the others around at the time,” said Dr Wills. “There’s even a link between average complexity within a group and the number of species alive today. “All organisms have a common ancestor, so that every living species is part of a giant family tree of life.”

Dr Adamowicz added: “With a few exceptions, once branches of the tree have separated they continue to evolve independently. Looking at many independent branches is similar to viewing multiple repeated runs of the tape of evolution. Our results apply to a group of animals with bodies made of repeated units. We must not forget that bacteria – very simple organisms – are among the most successful living things. Therefore, the trend towards complexity is compelling but does not describe the history of all life.”

Counterproductive Cameras At Traffic Lights
Researchers in Florida contend that cameras for catching drivers who run red lights actually increase accidents and injuries.

60-Second Science from Scientific American podcasts
12 March 2008

Scientists examining documents dating back 3,500 years say they have found proof that the origins of modern medicine lie in ancient Egypt and not with Hippocrates and the Greeks. The research team from the KNH Centre for Biomedical Egyptology at The University of Manchester discovered the evidence in medical papyri written in 1,500 BC – 1,000 years before Hippocrates was born.

"Classical scholars have always considered the ancient Greeks, particularly Hippocrates, as being the fathers of medicine but our findings suggest that the ancient Egyptians were practising a credible form of pharmacy and medicine much earlier," said Dr Jackie Campbell. "When we compared the ancient remedies against modern pharmaceutical protocols and standards, we found the prescriptions in the ancient documents not only compared with pharmaceutical preparations of today but that many of the remedies had therapeutic merit."

The medical documents, which were first discovered in the mid-19th century, showed that ancient Egyptian physicians treated wounds with honey, resins and metals known to be antimicrobial. The team also discovered prescriptions for laxatives of castor oil and colocynth and bulk laxatives of figs and bran. Other references show that colic was treated with hyoscyamus, which is still used today, and that cumin and coriander were used as intestinal carminatives. Further evidence showed that musculo-skeletal disorders were treated with rubefacients to stimulate blood flow and poultices to warm and soothe. They used celery and saffron for rheumatism, which are currently topics of pharmaceutical research, and pomegranate was used to eradicate tapeworms, a remedy that remained in clinical use until 50 years ago.

"Many of the ancient remedies we discovered survived into the 20th century and, indeed, some remain in use today, albeit that the active component is now produced synthetically," said Dr Campbell. "Other ingredients endure and acacia is still used in cough remedies while aloes forms a basis to soothe and heal skin conditions."

Fellow researcher Dr Ryan Metcalfe is now developing genetic techniques to investigate the medicinal plants of ancient Egypt. He has designed his research to determine which modern species the ancient botanical samples are most related to. "This may allow us to determine a likely point of origin for the plant while providing additional evidence for the trade routes, purposeful cultivation, trade centres or places of treatment," said Dr Metcalfe. "The work is inextricably linked to state-of-the-art chemical analyses used by my colleague Judith Seath, who specialises in the essential oils and resins used by the ancient Egyptians."

Professor Rosalie David, Director of the KNH Centre, said: "These results are very significant and show that the ancient Egyptians were practising a credible form of pharmacy long before the Greeks. "Our research is continuing on a genetic, chemical and comparative basis to compare the medicinal plants of ancient Egypt with modern species and to investigate similarities between the traditional remedies of North Africa with the remedies used by their ancestors of 1,500 BC."

Having a basic knowledge of scientific principles is no longer a luxury but, in today’s complex world, a necessity. And, according to a Michigan State University researcher, while Americans are holding their own, they are not even close to where they should be.

Participating at 3:45 p.m. PST today in an American Association for the Advancement of Science symposium, titled "Science Literacy and Pseudoscience," MSU’s Jon Miller said that Americans, while slightly ahead of their European counterparts when it comes to scientific knowledge, still have a long way to go.

"A slightly higher proportion of American adults qualify as scientifically literate than European or Japanese adults, but the truth is that no major industrial nation in the world today has a sufficient number of scientifically literate adults," he said. "We should take no pride in a finding that 70 percent of Americans cannot read and understand the science section of the New York Times." Approximately 28 percent of American adults currently qualify as scientifically literate, an increase from around 10 percent in the late 1980s and early 1990s, according to Miller’s research.

A professor in political science, Miller said one reason for the Americans’ slim lead is that the United States is the only major nation in the world that requires its college students to take general science courses. "Although university science faculties have often viewed general education requirements with disdain," he said, "analyses indicate that the courses promote civic scientific literacy among U.S. adults despite the disappointing performance of American high school students in international testing." Adding to the United States’ relatively good showing is Americans’ use of informal science education resources, such as science magazines, news magazines, science museums and the Internet.

Why is it important to have a population wise in the ways of science? Miller listed several reasons, including the need for a more sophisticated work force; a need for more scientifically literate consumers, especially when it comes to purchasing electronics; and, equally as important, a scientifically literate electorate who can help shape public policy.

"Over recent decades, the number of public policy controversies that require some scientific or technical knowledge for effective participation has been increasing," he said. "Any number of issues, including the siting of nuclear power plants, nuclear waste disposal facilities, and the use of embryonic stem cells in biomedical research point to the need for an informed citizenry in the formulation of public policy."

To be classified as "scientifically literate," Miller said one must be able to understand approximately 20 of 31 scientific concepts and terms similar to those that would be found in articles that appear in the New York Times weekly science section and in an episode of the PBS program "NOVA."

Laws of physics, math debunk Hollywood portrayals of ghosts, vampires

As the weather cools and Halloween approaches, chilling creaks in the stairs, bloodcurdling screams from the attic and other paranormal activity become more believable -- but not to UCF physics professor Costas Efthimiou.

The laws of physics and math debunk popular myths about ghosts and vampires, according to a paper published by Efthimiou and Sohang Gandhi, a UCF graduate now studying at Cornell University.

Using Isaac Newton's Laws of Motion, Efthimiou demonstrates that ghosts would not be able to walk and pass through walls. Basic math disproves the legend of humans turning into vampires after they are bitten, Efthimiou explains, because the entire human population in 1600 would have been wiped out in less than three years.

"These popular myths make for a lot of Halloween fun and great movies with special effects, but they just don't hold up to the strict tests of science," Efthimiou said.

In movies such as "Ghost," starring Patrick Swayze and Demi Moore, ghosts often walk like humans, pass through walls and pick up objects. But that portrayal cannot be accurate, Efthimiou says. For ghosts to have the ability to walk like humans, they would need to put a force upon the floor, which would exert an equal and opposite force in return. But ghosts' ability to pass through walls and have humans walk right through them demonstrates that they cannot apply any force.

Movies such as "Blade," featuring Wesley Snipes, suggest that vampires feed on human blood and that once a human has been bitten, he or she turns into a vampire and begins feeding on other humans. To disprove the existence of vampires, Efthimiou relied on a basic math principle known as geometric progression.

Efthimiou supposed that the first vampire arrived Jan. 1, 1600, when the human population was 536,870,911. Assuming that the vampire fed once a month and the victim turned into a vampire, there would be two vampires and 536,870,910 humans on Feb. 1. There would be four vampires on March 1 and eight on April 1. If this trend continued, all of the original humans would become vampires within two and a half years and the vampires' food source would disappear.

Efthimiou did not take into consideration mortality rates, which would have increased the speed at which the human population would have been vanquished. And even factoring in a birth rate would not change the outcome.

"In the long run, humans cannot survive under these conditions, even if our population were doubling each month," Efthimiou said. "And doubling is clearly way beyond the human capacity of reproduction."

Efthimiou also provides a practical explanation for "voodoo zombiefication," which suggests that zombies "come about by a voodoo hex being placed by a sorcerer on one of his enemies." He reviewed the case of a Haitian adolescent who was pronounced dead by a local doctor after a week of dramatic convulsions.

After the boy was buried, he returned in an incoherent state, and Haitians pronounced that a sorcerer had raised him from the dead in the state of a zombie.

Science, however, has a less-supernatural explanation. A highly-toxic substance called tetrodotoxin is found in a breed of puffer fish native to Haitian waters. Contact with this substance generally results in a rapid death. However, in some cases, the right dose of the toxin will result in a state that mimics death and slows vital signs to a level that is unable to be measured. Eventually, the victim snaps out of the death-like coma and returns to his or her regular condition.

Scientific analysis has shown that oxygen deprivation is consistent with the boy's brain damage and his incoherent state.

"It would seem that zombiefication is nothing more than a skillful act of poisoning," Efthimiou said.

23 October 2006
University of Central Florida

BERLIN (Reuters) - A German scientist has been testing an "anti-stupidity" pill with encouraging results on mice and fruit flies, Bild newspaper reported on Saturday.

It said Hans-Hilger Ropers, director at Max-Planck-Institute for Molecular Genetics in Berlin, has tested a pill thwarting hyperactivity in certain brain nerve cells, helping stabilise short-term memory and improve attentiveness.

"With mice and fruit flies we were able to eliminate the loss of short-term memory," Ropers, 62, is quoted saying in the German newspaper, which has dubbed it the "world's first anti-stupidity pill."

Sat Aug 5, 2006

News stories about medical research, often based on initial findings presented at professional conferences, frequently omit basic facts about the study and fail to highlight important limitations, warn Dartmouth researchers. Such omissions can mislead the public and distort the actual significance of the research, they caution. [read more]

Dartmouth Medical School News
6 June 2006